The technique uses a zinc finger nuclease, a protein that can break up pieces of DNA, to effectively inactivate the receptor gene.
What does ZFN stand for?
ZFN stands for Zinc Finger Nuclease (biotechnology)
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of ZFN
- Zona Franca de Manaus
- Zona Franca de Montevideo (Spanish: Montevideo Frank Zone; Uruguay)
- Zone de Forte Mixité (French: Strong Mixed Zone; Belgium)
- Zambia Fisheries and Marketeers Union
- Exiled Former Members of UNA - Denton (defunct)
- Zentrum Fuer Neurowissenschaften (German: Center for Neuroscience; University of Freiburg; Germany)
- Zentrum Fuer Niederdeutsch (German: Center for Low German; Ratzeburg, Germany)
- Zentrum für Netze (German: Center for Networks; University of Bremen; Bremen, Germany)
- Zero order, Fixed corridor, Non-redundant Sample Transmission
- Zions First National Bank
- Zeitschrift Fuehrung Organisation (German: Magazine Leadership Organization; journal)
- Zeitschrift Fuer Ostmitteleuropa-Forschung (German: Journal for Research on East Central Europe; Herder Institute)
- Zona-Free Bovine Oocytes (reproduction)
- Zone Française d'Occupation (French: French Zone of Occupation; World War II)
- Zero-Filled on Demand (Linux program)
- Zachodniopomorskiego Forum Organizacji Pozarzadowych (Polish: West Non-Governmental Organization Forum)
- Zoom Field of View (aviation)
- Zero-Flag Propagation
- Zero-Flow Pressure (anesthesia)
Samples in periodicals archive:
The new technique employs zinc finger nuclease (ZFN) proteins, which can bind and cut DNA at precisely defined locations in the genome.
With molecular editors called zinc finger nucleases, scientists correct a mutation in mice that leads to hemophilia (SN: 7/30/11 p.
Working with newborn mice, researchers led by Katherine High at the Children's Hospital of Philadelphia found that molecular editors called zinc finger nucleases can correct a genetic mutation that leads to the blood-clotting disorder hemophilia.
For the study, the researchers created a customized enzyme called a zinc finger nuclease (ZFN) to change single genes in tobacco plant cells.