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What does XIAP stand for?

XIAP stands for X-linked Inhibitor of Apoptosis

This definition appears frequently and is found in the following Acronym Finder categories:

  • Science, medicine, engineering, etc.

Samples in periodicals archive:

The study, entitled "A Phase 2, Multicenter, Open-Label, Randomized Study of the X-Linked Inhibitor of Apoptosis (XIAP) Antisense AEG35156 Given In Combination With Carboplatin/Paclitaxel or the Combination of Carboplatin/Paclitaxel Alone In Patients With Advanced Non Small Cell Lung Cancer" is being conducted in the United States in collaboration with U.
Aegera has taken this technology to the clinic with an antisense therapeutic, AEG35156, targeting just one of their IAPs named the X-linked inhibitor of apoptosis (XIAP) protein, a target which inhibits apoptosis using duel mechanisms.
SNS-032 acts by inhibiting the activity of CDKs 7 and 9 and reducing RNA synthesis, as well as down-regulating the expression of anti-apoptotic proteins, such as myeloid cell leukemia sequence 1, or MCL-1, and X-linked Inhibitor of Apoptosis Protein, or XIAP, both of which are associated with CLL-cell survival and proliferation.