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What does uE3 stand for?

uE3 stands for Unconjugated Estriol (abnormal pregnancy screening)

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  • Science, medicine, engineering, etc.

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Samples in periodicals archive:

Studies have found that hCG testing alone can detect 40% of Down syndrome cases in the second trimester, while the addition of AFP and unconjugated estriol increases the sensitivity to 60%, and inhibin A further elevates the detection rate to 70%.
For example, microparticle enzyme immunoassay has errors in estradiol measurements due to interference from unconjugated estriol.
Patients in the highest risk group (greater than 1:30 risk in this study) undergo CVS, those in the lowest risk group (less than 1:1,500 risk) receive no further testing, and those in the borderline risk group (between 1:30 and 1:1,500 risk) undergo quad screening (serum alpha feto-protein, hCG, unconjugated estriol, and inhibin A) in the second trimester and receive a final risk assessment based on all the measures, with a risk cutoff for further testing of 1:270, Dr.
The quadruple test calculates the risk of a Down syndrome term pregnancy based on the maternal age and concentration of four markers in maternal serum--alpha-fetoprotein, unconjugated estriol, human chorionic gonadotropin and inhibin-A--at weeks 14 to 22 of the pregnancy.
An analysis of the effect of analytical imprecision in the 2nd-trimester triple test [a-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3)] showed that individual patient risk figures can change dramatically owing to compounding effects of errors in each of the 3 component test measurements (8).