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What does UPS stand for?

UPS stands for Ubiquitin-Proteasome System

This definition appears frequently and is found in the following Acronym Finder categories:

  • Science, medicine, engineering, etc.

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We have 209 other meanings of UPS in our Acronym Attic

Samples in periodicals archive:

10) Clearing misfolded mutant protein and inhibiting aggregate formation Decreasing mutant protein levels may also be achieved by enhancing polyQ protein clearance, through upregulation of the two main cellular pathways responsible for degradation of misfolded proteins--the ubiquitin-proteasome system (UPS) and autophagy.
Neuronal cell adhesion molecules "are critical in the development of the nervous system, contributing to axonal guidance, synaptic formation and plasticity, and neuronal-glial interactions," the researchers explained, while the ubiquitin-proteasome system "operates pre- and post-synaptic compartments, regulating synaptic attributes, including transmitter release, synaptic vesicle recycling in pre-synaptic terminals, and dynamic changes in dendritic spines and the post-synaptic density.
The ubiquitin-proteasome system mediates protein recycling by tagging abnormal or unwanted proteins within cells with the small protein ubiquitin.