| TC | Total Chances (baseball statistics) | |
| TC | Technical Committee | |
| TC | Transport Canada | |
|
| TC | Thread Count (fabric) | |
| TC | Teachers College | |
| TC | Thompson/Center (gun company) | |
| TC | Technical Communication | |
| TC | Twin Cam | |
| TC | Total Commander (file manager software) | |
| TC | Total Cholesterol | |
| TC | Telecommunications | |
| TC | Type Certificate | |
| TC | Transfer Case (vehicle auxiliary 4WD transmission) | |
|
| TC | Technical Cooperation | |
| TC | Take Care | |
| TC | Traffic Control | |
| TC | Terms & Conditions (law) | |
| TC | Tissue Culture | |
| TC | United Arab Emirates | |
| Tc | Case Temperature | |
| TC | Total Cost | |
| TC | Twin Cities (Minnesota) | |
| TC | Time Code | |
| TC | Turks and Caicos Islands (ISO country code) | |
| TC | Time Capsule | |
| TC | Time Capsule (Apple backup appliance) | |
| TC | Temperature Control | |
| TC | Tax Court | |
| TC | Training Camp | |
| TC | Technology Center | |
| TC | Traditional Chinese (language) | |
| TC | Town and Country | |
| TC | Tungsten Carbide (materials) | |
| TC | Temperature Controller | |
| TC | The Cure (UK band) | |
| TC | Track Changes | |
| TC | Technical Center | |
| TC | Therapeutic Community | |
| TC | Truck Camper | |
| TC | Tax Credit | |
| TC | Tropical Cyclone | |
| TC | Tribunal Constitucional (Portuguese constitutional court) | |
| Tc | Technetium | |
| TC | Traction Control | |
| TC | Tom Cruise | |
| TC | Thin Client (computer hardware) | |
| TC | Teleconverter (photography lens) | |
| TC | Tinned Copper (various companies) | |
| TC | Town Centre (Age of Empires II game) | |
| TC | Time Clock | |
| TC | Tom Clancy (author) | |
| TC | Total Compensation | |
| TC | Training Centre (see CGTC) | |
| TC | Trinity College | |
| TC | Team Captain | |
| TC | Tri-Cities (Washington) | |
| TC | Tetracycline | |
| TC | Critical Temperature | |
| TC | Thermal Conductivity | |
| TC | Test Case (testing methodology) | |
| TC | Thermocouple | |
| TC | The Clash (band) | |
| TC | Tachycardia | |
| TC | Testicular Cancer | |
| TC | Time Constant | |
| TC | Toxic Chemical (hazardous chemicals) | |
| TC | Total Carbon (TIC + TOC) | |
| TC | Top Cat | |
| TC | Turbo Coupe (Ford Thunderbird Model) | |
| TC | Time Crisis (gaming) | |
| TC | Temperature Coefficient | |
| TC | Total Conversion (computer games) | |
| TC | Transmission Control | |
| TC | Torque Converter (automotive automatic transmission) | |
| TC | Temple City (California) | |
| TC | Telecine | |
| TC | Technology Company | |
| TC | Treatment Center | |
| TC | Technology Corporation | |
| TC | Training and Certification | |
| TC | Telephone Call | |
| TC | Toner Cartridge | |
| TC | Tesla Coil | |
| TC | That's Cool | |
| TC | Trusted Computing | |
| TC | The Conquerors (Microsoft Age of Empires expansion pack) | |
| TC | Transportation Company (US Army) | |
| TC | Textual Criticism (biblical texts) | |
| TC | Transaction Code | |
| TC | Transfer Credit (education) | |
| TC | Transcontinental | |
| TC | Tax Code | |
| TC | Technical Characteristics | |
| TC | Trading Card | |
| TC | Time Check | |
| TC | Turbo Cache (computing) | |
| TC | Time Charter (shipping term) | |
| TC | Traditional Classroom (education) | |
| TC | Terry Collins (baseball manager) | |
| TC | Terminal Contact (gait cycle) | |
| TC | Too Cool | |
| TC | Tracking Camera | |
| TC | Transitive Closure | |
| TC | Air Tanzania (IATA airline code) | |
| Tc | Core Temperature | |
| TC | Terapia Celular (Spanish: Cellular Therapy) | |
| TC | Trilateral Commission | |
| TC | Toxicity Characteristic | |
| TC | Texarkana College (Texarkana, Texas, USA) | |
| TC | Thermal Cycling (accelerated life test) | |
| TC | Tronc Commun | |
| TC | Thermal Control | |
| TC | Topology Change (Cisco) | |
| TC | Take Cover | |
| TC | Tusculum College (Greeneville, TN) | |
| TC | Tell City (Indiana) | |
| TC | Total Credit (distributive computing; tax calculations) | |
| TC | Traffic Calming (devices) | |
| TC | Truck Company | |
| TC | Therapeutic Cloning (genetics) | |
| TC | Test Control | |
| TC | Transaction Coordinator (real estate) | |
| TC | Technician Certificate (UK) | |
| TC | Trace Cache | |
| TC | Tical (former currency of Thailand) | |
| TC | Tropic of Cancer | |
| TC | Thrust Chamber | |
| TC | Tierra Comunera (Castilian Nationalist Party) | |
| TC | Training Coordinator | |
| TC | Tank Commander | |
| TC | Test Coverage | |
| TC | Trust Center (informatics) | |
| TC | Telecommand | |
| TC | Turkiye Cumhuriyeti (Republic of Turkey) | |
| TC | Transportation Command | |
| TC | Tropic of Capricorn | |
| TC | Transportation Corps | |
| TC | Traffic Collision | |
| TC | Technical Coordinator | |
| TC | Traffic Camera | |
| TC | Technology Coordinator | |
| TC | Tom Cat | |
| TC | Total Coliforms | |
| TC | Thiokol Corporation (est. 1929) | |
| TC | Thundercracker | |
| TC | Transmission Convergence (ATM) | |
| TC | Time Capture | |
| TC | Tactical Communications | |
| TC | Trellis Coded | |
| TC | TinyChat (Internet chat system) | |
| TC | Training Circular | |
| TC | Type Classification | |
| TC | Technical Centre | |
| TC | Transportation Coordinator | |
| TC | Technology Commercialization | |
| TC | Trial Counsel | |
| TC | Terminal Count | |
| TC | Transaction Capabilities | |
| TC | Total Communication (concept for teaching deaf children) | |
| TC | Tetoron Cotton (fabric) | |
| TC | Toronto Creatives (Toronto, Canada) | |
| TC | Traffic Conditioner | |
| TC | Tidal Current | |
| TC | Tantalum Capacitor | |
| TC | Teacher Consultant | |
| TC | Toxic Concentration (TC50 = 50% of the population or TClo = low) | |
| TC | Team Chief (aerospace) | |
| TC | Tarif de Convention (French: Tariff Convention; France) | |
| TC | Telecommunications Council | |
| TC | Ticket Collector | |
| TC | Tri-Clover | |
| TC | Transit Corridor | |
| TC | Trouble Call | |
| TC | Turbo Code | |
| TC | Telecommunities Canada | |
| TC | Temperature Compensating | |
| TC | Terminal Controller | |
| TC | Transit Case | |
| TC | Troop Commander | |
| TC | Triple Champion | |
| TC | Target Concentration | |
| TC | Traveler's Check | |
| TC | Tougaloo College (Jackson, MS) | |
| TC | Twin Carbs | |
| TC | Transcanadienne (road across Canada) | |
| TC | Thermal Cutting (welding) | |
| TC | Test Component (TTCN) | |
| TC | Transportation Code | |
| TC | Triple Crochet | |
| TC | Trabuco Canyon (California) | |
| TC | Time Cube | |
| TC | Trusteeship Council (UN) | |
| TC | Telefilm Canada | |
| TC | Tentative Consensus | |
| TC | Text Corpora (Project) | |
| TC | Test Controller | |
| TC | Tasa de Cambio (Spanish) | |
| TC | Test Conductor | |
| TC | Toll Center | |
| TC | Transaction Count | |