We therefore investigated the effect of testosterone on the gene expression of apolipoprotein A-I (apoA-I), hepatic lipase (HL), scavenger receptor B1 (SR-BI), and the ATP binding cassette transporter A1 (ABCA1), all of which are important regulators of HDL metabolism.
What does SR stand for?
SR stands for Scavenger Receptor
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of SR
We have 157 other meanings of SR in our Acronym Attic
- Santa Rosa (California)
- Sarcoplasmic Reticulum
- Satellite Radio
- Satellite Receiver
- Saturable Reactor
- Saturday Review
- Saudi Riyal (national currency)
- Savannah River
- Scan Ratio
- Scanning Radiometer
Samples in periodicals archive:
Researchers have developed a simple blood test for this variation of the scavenger receptor class B type 1 gene (SCARB1) but emphasized there is no approved therapy yet to address the problem in infertile women.
Pivotal advance: Activation of cell surface Toll-like receptors causes shedding of the hemoglobin scavenger receptor CD163.
Colesevelam significantly increased hepatic gene expression for scavenger receptor type BI, apolipoprotein A1, LCAT, cholesterol ester transfer protein, cholesterol 7-[alpha]-hydroxylase (CYP7A1), low-density lipoprotein receptor, and liver X receptor (LXR).
For example, macrophages sport a class of proteins called scavenger receptors that enable the cells to bind to and take up a variety of lipids.
Direct CMV infection may also enhance uptake of oxidized low-density lipoprotein by macrophages and smooth muscle cells, promoting foam cell development; through its immediate-early gene products, CMV may increase uptake of modified low-density lipoprotein and stimulate type A scavenger receptor gene expression by smooth muscle cells (54).
Testosterone up-regulates scavenger receptor BI and stimulates cholesterol efflux from macrophages.