| S/B | Should Be | |
| SB | Should Be | |
| SB | Subject | |
|
| SB | Santa Barbara | |
| SB | Super Bowl (US football championship game) | |
| SB | Small Block (auto engine) | |
| SB | Small Business | |
| SB | Symbols (assembly language ASM51 assembler control) | |
| SB | Senate Bill (in state legislatures) | |
| SB | Sound Blaster | |
| SB | Service Bulletin | |
| SB | Stolen Base (baseball) | |
| SB | Sandy Bridge (Intel Corp.) | |
| SB | South Bend (Indiana) | |
| SB | Somebody | |
| SB | Spring Break | |
|
| SB | School Bus | |
| SB | Substitute (sports) | |
| SB | Bachelor of Science | |
| SB | Seat Belt | |
| SB | San Bernardino (California) | |
| SB | Scoreboard | |
| SB | South Bay (California) | |
| SB | Sit Back | |
| SB | Stony Brook (SUNY) | |
| SB | Small Blind (poker) | |
| SB | Srimad Bhagavatam (Puranic scripture) | |
| SB | Solomon Islands (ISO country code, top level domain) | |
| SB | SpongeBob (SpongeBob SquarePants cartoon character) | |
| SB | Saarbrücken (German city) | |
| SB | Standby | |
| SB | Student Body | |
| SB | Antimony (Stibium) | |
| SB | Season Best (athletics scoring) | |
| SB | Sunset Beach | |
| S/B | Seen By (UK medical reporting) | |
| SB | Sound Board | |
| SB | Sonic Boom | |
| SB | Starbucks (coffee shop) | |
| SB | SuperBike (motorcycling) | |
| SB | System Builder | |
| SB | South Beach (Miami, FL) | |
| SB | Switchboard | |
| SB | Strong Bad (Homestarrunner.com character) | |
| SB | Shaw Brothers (Kung-Fu film producers) | |
| SB | Soybean | |
| SB | Smash Bros (game) | |
| SB | Spybot (Search & Destroy) | |
| SB | Sandra Bullock (actress) | |
| SB | Southern Baptist | |
| SB | Starbase (gaming) | |
| S/B | Standby | |
| SB | St. Pierre & Miquelon | |
| SB | South Bridge | |
| SB | Sandy Beach (Camp Yawgoog, BSA) | |
| SB | Student Book | |
| SB | Security Breach | |
| SB | Skate Boarding | |
| SB | Small Bowel | |
| SB | Storyboard | |
| S/B | Southbound (traffic/transportation) | |
| SB | Star Bulletin (Honolulu newspaper) | |
| SB | Service Bureau | |
| SB | Southwestern Bell (telephone) | |
| SB | Small Boat | |
| SB | Shadowbane (online game) | |
| SB | Space Bar | |
| SB | Sarah Brightman (musician) | |
| SB | So Bored | |
| SB | Skybox (cards) | |
| SB | Sunset Boulevard (movie) | |
| SB | SkyBlade (gaming) | |
| SB | Space-Based | |
| SB | Slow Burn | |
| SB | Sexy Beast (TV show) | |
| SB | Special Branch (Met Police, London) | |
| SB | South Bound | |
| SB | Sex Bomb | |
| SB | Sexy Beach (game) | |
| SB | Side Band | |
| SB | Sirius Black (Harry Potter) | |
| SB | Selbstbedienung (German: self service) | |
| S/B | swing/by | |
| SB | Sodium Benzoate | |
| SB | Spoiled Brat | |
| SB | SONICblue (electronics company) | |
| SB | Stealth Bomber | |
| SB | Symphonic Band | |
| SB | Spaceballs (Mel Brooks movie) | |
| SB | Sonic Battle (game) | |
| SB | Syndicate Bank (India) | |
| SB | Supply Bulletin | |
| Sb | Stibium (Antimony) | |
| SB | Soft Ball | |
| SB | Smoke Break | |
| SB | Self-Booting (CD) | |
| SB | Superintendencia de Bancos (Spanish) | |
| SB | SuperBrawl (World Championship Wrestling event) | |
| SB | Sustainment Brigade (US Army) | |
| SB | Serum Bilirubin | |
| SB | Softbound | |
| SB | Slow Blow (type of electric fuse) | |
| SB | Sistema Bancario (Guatemala) | |
| SB | Sangguniang Bayan | |
| SB | Sick Bay (military) | |
| SB | Strictly Business | |
| SB | Selection Board | |
| SB | Smart Bomb | |
| S/B | Signal to Background (ratio) | |
| SB | Sinus Bradycardia | |
| SB | Stilb (CGS unit) | |
| SB | Stock Book (philately) | |
| SB | Star Base (Star Trek) | |
| SB | Sin Banderas (musical group) | |
| SB | Shot Blocked (basketball) | |
| SB | Sub-Basement | |
| SB | Sawyer Brown (country music artist) | |
| SB | Session Bean (Enterprise JavaBean) | |
| S/B | Switch Board | |
| SB | Stem Borer | |
| SB | Surface Barrier | |
| SB | System Busy (Nortel) | |
| SB | Service Battalion | |
| SB | Status Board | |
| SB | Secondary Branches | |
| SB | Spirit Breaker (Dota Hero, game) | |
| SB | SuperBoard | |
| SB | Safe Berth | |
| SB | Surface Burning | |
| SB | Security Blankets | |
| SB | Sauble Beach (Ontario, Canada) | |
| SB | Soul Blazer (gaming) | |
| SB | Straight Bond | |
| SB | Still Birth | |
| SB | StatBar (website) | |
| SB | Surveillant de Baignade (French: Lifeguard) | |
| SB | Société de Biologie (French: Biology Society) | |
| SB | Shotgun Blues (Guns N' Roses song) | |
| SB | Squirrel Bait (band) | |
| SB | Sort Buffer | |
| SB | Sinai Beach (band) | |
| SB | Simultaneous Broadcast | |
| SB | Salary Band | |
| SB | Salcobrand (pharmacy; Chile) | |
| SB | Sync Byte (ITU-T) | |
| SB | Surface Burst | |
| SB | Signal Battery | |
| SB | Shiny Beast (band) | |
| S/B | Soil/Bentonite | |
| SB | Standard Babylonian | |
| SB | Sequence Breaking (video games) | |
| SB | Suggested Bid | |
| SB | South Buffalo Railway Company | |
| SB | Sweater Boy | |
| SB | Scleral Buckling Procedure (ophthalmology) | |
| SB | Sentinel Byte | |
| SB | Standby Base | |
| SB | Super Byte | |
| SB | Sphere Bound | |
| SB | Smile Brigade (band) | |
| SB | Air Caledonie International, New Caledonia (IATA airline code) | |
| SB | Steelbeak (Disney Character) | |
| SB | Scotia Band (Scotia, CA) | |
| SB | Seventh Barrier (gaming clan) | |
| SB | Sonic Bilby | |
| SB | Solarbotics Ltd. (robot company) | |
| SB | Seva Bharati (Orissa, India) | |
| SB | Symmetry Braking | |
| SB | SveskeBanden (Danish online gaming league) | |
| SB | Skip Briefing (gaming) | |
| SB | Shippensburg Band (Shippensburg, PA) | |
| SB | Side Bend/ing | |
| SB | Spanish Booster (language services) | |
| SB | Stamford Baffles | |
| SB | Short Along Bit Lines | |
| SB | Sea-Based Strategic Warfare | |
| SB | Synchronizing Busbar | |
| SB | Steve Biko/Bantu (symbol of black resistance to the Apartheid regime) | |
| SB | Summerfest Boyz | |
| SB | Spam Breaker | |
| SB | Spina Bifida | |
| SB | Speed Brake | |
| SB | Stand Bold | |
| SB | Spousal Benefit | |
| SB | SmithKline Beecham (UK) | |
| SB | Software Business | |
| SB | Sengoku Basara (video game) | |
| S/B | Starting Bid (trade) | |
| S/B | Sand Blast | |
| SB | Silver Bullet (various meanings) | |
| SB | Shipping Bill (various organizations) | |
| SB | Shoot Boxing (Japan) | |
| SB | Seventeen or Bust (distributed computing project) | |
| SB | Serene Byte | |
| SB | Super Balance | |
| SB | Superboy | |
| SB | Strong Base Ion Exchange | |
| SB | Structural Biology (various schools) | |
| SB | Sugar Baby | |
| SB | StarBattle (gaming) | |