In the primary efficacy analysis of the Phase 2 study, all doses showed improvement in median pulmonary vascular resistance (PVR).
What does PVR stand for?
PVR stands for Pulmonary Vascular Resistance
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of PVR
We have 108 other meanings of PVR in our Acronym Attic
- Potential Vertical Rise
- Precision Voltage Reference
- Premature Voluntary Release
- Priya Village Roadshow (India cinema)
- Process Variation Reduction
- Product Verification Review
- Programmable Virtual Router
- Programmable Voltage Regulator (microcontroller)
- Proliferative Vitreoretinopathy (ophthalmology)
- Puerto Vallarta, Jalisco, Mexico - Gustavo Diaz Ordaz (Airport Code)
- Pulse Volume Recording
- Passive Variable Respiratory-Minute-Volume Based Addition Semi Closed (rebreather)
- Pennsylvania Voter Registration Act (law)
- Physical Volume Reserved Area
- Pioneer Valley Radio Association (Connecticut)
- Plant Variety Rights Act 1987 (New Zealand)
- Poway Valley Riders Association (horseback riding; est. 1960; Poway, CA)
- Platform Vlieghinder Regio Castricum (Netherlands)
- Pleasant View Retirement Community (Manheim, PA)
- Point of Vertical Reversing Curve
Samples in periodicals archive:
While the guidelines recommend against targeted therapies for RHC-confirmed PH, a trial of either a prostanoid or an endothelin-receptor antagonist is recommended for patients with confirmed PH and elevated pulmonary vascular resistance, normal pulmonary capillary wedge pressure, and related symptoms.
Cardiac catheterization is rarely indicated and reserved for patients who present after early infancy and, therefore, are at risk for elevated pulmonary vascular resistance, or any patient in whom the anatomy cannot be adequately defined by echocardiography.
A study using losartan in PAH secondary to chronic obstructive pulmonary disease was also in the acute setting and oral dosing with losartan (50 mg) produced a significant reduction in mean PAP and total pulmonary vascular resistance (8).
Pulmonary arterial hypertension (PAH) is characterized by elevated pulmonary vascular resistance that subsequently leads to right heart failure.
Traditionally, pulmonary arterial hypertension is thought of as a disease of the peripheral lung vasculature, wherein excessive vasoconstriction and/or structural remodeling of the small pulmonary blood vessels are the major contributors to increased pulmonary vascular resistance and right ventricular overload.
This agent also has produced a decrease in pulmonary vascular resistance and an improvement in the six-minute walk test.
2) Right-heart catheterization allows pressures and cardiac output to be accurately measured, and pulmonary vascular resistance to be calculated.