When these normal cellular prion precursors convert to pathogenic prion proteins, the transmissible conformations are characterized by [beta]-pleated sheets rather than the normal [alpha]-helix structure, and they do not elicit an immune response (4).
What does PRP stand for?
PRP stands for Prion Protein
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of PRP
We have 329 other meanings of PRP in our Acronym Attic
- Preferred Risk Policy (flood insurance)
- Preferred Risk Program (insurance)
- Prejudice Reduction Program
- Preliminary Restoration Plan (US Army)
- Premium Recycled Parts
- Premium Reinforcement Pulp (paper and pulp industry)
- Previously Rented Product
- Primary Residential Parent
- Prime Power (various companies)
- Prince's Rainforests Project (UK)
- Prior Reference Price
- Probability and Random Processes (mathematics; book)
- Probability Ranking Principle (information retrieval)
- Probable Prime (mathematics; number theory)
- Problem Resolution Program (IRS)
- Product Realization Process
- Product Replacement Plan (2 year replacement product plan offered at Best Buy stores)
- Production Readiness Plan
- Production Requirements Plan (US Navy)
- Productivity Retention Program
Samples in periodicals archive:
They then tested whether infectious prion proteins retained the ability to misfold normal proteins in vitro.
RT-QuIC, developed in recent years, detects when normal prion protein converts to an abnormal form The resulting test-which they call enhanced QuIC (eQuIC)-improves prospects for routinely detecting low levels of abnormal prions in tissues, fluids or environmental samples such as soil.
To date, every person confirmed as having vCJD has had a particular "homozygous" form of the human prion protein gene known as MM.
But scientists from the Medical Research Council stopped the spread of disease by genetically switching off production of normal prion protein.
Prion protein is a natural cellular protein that can become misfolded into infectious particles and cause bovine spongiform encephalopathy (BSE, or "mad cow disease") and a lethal variant of Creutzfeldt-Jakob disease (vCJD) in humans.
22 Kyodo (EDS: UPDATING WITH RELEASE OF STUDY AT SOCIETY IN 2ND GRAF) A team of researchers said Tuesday that they recently succeeded in delaying the onset of symptoms of prion disease, widely known for brain-wasting effects in mad cow disease, by inoculating mice with normal prion proteins taken from other animals.