Printer friendly
"AcronymFinder.com

What does PRR stand for?

PRR stands for Pattern Recognition Receptor (immunology)

This definition appears frequently and is found in the following Acronym Finder categories:

  • Science, medicine, engineering, etc.

See other definitions of PRR

Other Resources:
We have 134 other meanings of PRR in our Acronym Attic

Samples in periodicals archive:

SP-A and SP-D are present in pulmonary epithelial lining fluid; they are produced by type II pneumocytes and Clara cells and belong to the pattern recognition receptor family of C-type lectins, which bind to surface carbohydrates on microbial pathogens and promote their phagocytosis by alveolar macrophages.
More recently toll like receptors (TLRs), the pattern recognition receptors that regulate innate immunity and microbial tolerance, have been shown to be dysregulated in IBS.
These receptors were later named pattern recognition receptors or PRRs because they have the ability to recognize molecules that occur across species in a large class of disease-causing microbes.
Appropriate areas of research include, but are not limited to: 1) Characterization of host cells involved in the innate immune response to protozoa; 2) Identification of novel pathogen-associated molecular pattern recognition receptors on host cells; 3) Characterization of mediators of innate immunity that are produced by host cells stimulated by protozoa; 4) Elucidation of the intracellular signaling pathways in the mammalian innate immune cells that are stimulated by protozoa; 5) Comparison of human versus animal model molecular responses to protozoan pathogens or their components; 6) Human or animal model gene mutations or polymorphisms associated with distinctive innate immune responses to protozoa.
Recent research has indicated that it stimulates the Toll-like receptor 2, also known as a pattern recognition receptor, present on macrophages that normally enables the cell to recognize invading pathogens, according to the article.