Apparently, to gain access to the bloodstream, tumor cells may not need to have particular phenotypic traits, for example, a high nuclear to cytoplasmic ratio.
What does N/C stand for?
N/C stands for Nuclear to Cytoplasmic
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They demonstrated low to moderate nuclear to cytoplasmic (N:C) ratios and a generous cytoplasmic domain (Figure 1, A and B).
[FIGURE 1 OMITTED] [FIGURE 2 OMITTED] [FIGURE 3 OMITTED] Many of the cytologic features (scalloped borders of cell clumps, intercellular windows, with lighter dense cytoplasm edges, and low nuclear to cytoplasmic ratios) are shared between reactive and malignant epithelioid mesothelial cells.