The synthetic analogues of L-arginine that are known to decrease NO concentration by inhibiting nNOS and eNOS are N-nitro-L-arginine methyl ester (L-NAME) and N-nitro-L-arginine (L-NA), N-monomethyl-L-arginine (L-NMMA) (1), and the nitro-indazole compound, 7-nitroindazole (7-NI) (16) are known to inhibit NO synthesis in the brain.
What does LNAME stand for?
LNAME stands for N-Nitro-L-Arginine Methyl Ester
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Samples in periodicals archive:
[FIGURE 8 OMITTED] To assess whether NOS is responsible for the generation of NO, we used the specific antagonist N-nitro-L-arginine methyl ester (L-NAME), which is known to block NOS activation in pancreatic islets (Akesson et al.