Palliative treatment was started with oral Methylprednisolone 1 mg/kg body weight, Mercaptopurine and monthly courses with Cytosine arabinoside 75 mg/[m.
What does 6-MP stand for?
6-MP stands for Mercaptopurine
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Samples in periodicals archive:
Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity.
Thiopurines are a class of drugs that include azathioprine and mercaptopurine.
Researchers also found low MSH2 levels were associated with leukemia resistance to the thiopurine medications, including mercaptopurine, a drug all children with ALL receive.
Key words ALL--Indian population--polymorphism--SNaPshot--TPMT ********** Thiopurine methyltransferase (TPMT) is a cytosolic enzyme that catalyzes the S-methylation of aromatic and heterocyclic sulfhydryl compounds, including mercaptopurine (MP), thioguanine (TG), and azathioprine (AZA) (1).
Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus.
However, febuxostat is contraindicated in patients who are taking azathioprine, mercaptopurine, and theophylline.
Molecular diagnosis of thiopurine Smethyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance.