It is caused by the lack of an enzyme called homogentisic dioxygenase which means that patients cannot fully break down a toxic acid called homogentisic acid (HGA).
What does HGA stand for?
HGA stands for Homogentisic Acid
This definition appears frequently and is found in the following Acronym Finder categories:
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See other definitions of HGA
We have 69 other meanings of HGA in our Acronym Attic
- Hercules Graphics Adapter
- High Grade Algorithm
- High Growth Area
- High-Gain Antenna
- High-Speed Graphics Assembly
- Higher Grade Assistant (Life Insurance Corporation of India)
- Higher Ground Academy (Minnesota)
- His Glory Alone (Christian rap group)
- Hokkaido Golf Association (Japan)
- Holy Guardian Angels (Reading, PA catholic church)
- Honor Guard Academy
- Hop Growers of America (Moxee, WA)
- Host Government Agreement (foreign investing)
- Houston Golf Assossiation (Houston, TX)
- Human Genetics Alert (watchdog group; London, UK)
- Human Granulocytic Anaplasmosis (infectious disease)
- Human Great Ape
- Human Growth Agent
- High Gain Antenna, Helical Type (S-Band)
- High Gain Antenna, Horn Type (X-Band)
Samples in periodicals archive:
19] In melanotic RCC, dark-brown endogenous pigments can be found; the kidney may appear black one, and the differential diagnosis may be hemosiderin, homogentisic acid and lipofuscin.
Alkaptonuria is a rare metabolic disorder in the phenylalanine and tyrosine catabolic pathway which is characterized by the excessive excretion of homogentisic acid in the urine, ochronosis, and debilitating arthritis of the spine and large joints.
Fifteen standard phenolic compounds, including gallic acid, pyrogallol, homogentisic acid, protocatechuic acid, (+) catechin, chlorogenic acid, caffeic acid, vanillin, ferulic acid, naringin, resveratrol, naringenin, hesperetin, formononetin, biochanin-A were purchased from Sigma Aldrich and used for calibration curves.
Sbou' explained that Alkaptonuria is caused by deficiency of the enzyme homogentisic acid oxidase (HGO), as a consequence of the enzymatic block, the homogentisic acid (HGA) accumulates in body tissues, vertebrae, joints and heart valves,.
Importantly, neither melanin nor homogentisic acid are detected in a routine urinalysis, therefore careful attention to the color of urine can provide an important clue to an underlying disease process.
homogentisic acid, glycerol, glutaric acid, and others).
Patients do not have enough of the enzyme homogentisic acid oxidase, which causes acid to build up in the body.