The spindle cells were negative for melanin A, HMB-45, epithelial membrane antigen, pankeratin, muscle actin, CD 117, low-molecular-weight keratin, high-molecular-weight keratin, CD34, CD5, factor VIIIa, and CD45/leukocyte common antigen.
What does HMWK stand for?
HMWK stands for High-Molecular-Weight Keratin (kidney cancer indication)
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- high-molecular-weight protein
Samples in periodicals archive:
Recently, in a report on spindle cell malignant neoplasms on sun-damaged skin, the authors advocated the use of high-molecular-weight keratin as a sensitive and specific marker for spindle cell squamous cell carcinoma.
10) The results of staining with high-molecular-weight keratin are somewhat more variable, as 75 to 95% of the cells stain positively.