The majority of women with hereditary breast and ovarian cancer have a mutated form of the BRCA1 or BRCA2 genes, which normally suppress the growth of breast and ovarian tumours.
What does HBOC stand for?
HBOC stands for Hereditary Breast and Ovarian Cancer
This definition appears frequently and is found in the following Acronym Finder categories:
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See other definitions of HBOC
We have 19 other meanings of HBOC in our Acronym Attic
- Humboldt, Nebraska (airport code)
- Hyperbaric Oxygen
- Hyperbaric Oxygenation
- Hierarchical Bayesian Optimization Algorithm
- Honda Battle of the Bands (marching band exhibition)
- Harbor Boulevard of Cars
- Hawke's Bay Orienteering Club (New Zealand)
- HBO & Co of Georgia
- Hemoglobin Bovine Oxygen Carrier
- Hemoglobin-Based Oxygen Carrier
- Horse Breeders and Owners Conference
- Hunter Bird Observers Club
- Hemoglobin-Based Oxygen-Carrying Solution
- Hudson's Bay Oil and Gas Company, Limited (est. 1929; Canada)
- Harbor Branch Oceanographic Institution (Florida)
- Het Begon Op Klompen (Dutch: It Started on Clogs; Dutch football club)
- Honey Bunches of Oats (breakfast cereal)
- Home Box Office Plus (East) (pay cable network)
- Home Box Office Plus West
- Handboek Beheer Openbare Ruimte (handbook for maintenance of public space)
Samples in periodicals archive:
Mutations of the BRCA1 and BRCA2 genes have been linked to the development of hereditary breast and ovarian cancer.
Both BRCA1 and BRCA2 are genes that are linked with hereditary breast and ovarian cancers.
An AstraZeneca spokesman said development was still at the "very early stages" but that it was envisaged the compound could be used to treat woman with hereditary breast and ovarian cancer.
Scientists already know that inheriting faulty BRCA genes can trigger hereditary breast and ovarian cancer, but they did not know what role these genes had in sporadic cancer.
The most prevalent hereditary syndromes associated with these tumors (Table) are hereditary nonpolyposis colorectal cancer (HNPCC), familial adenomatous polyposis (FAP), hereditary breast and ovarian cancer (HBOC), and multiple endocrine neoplasia type 2 (MEN 2).
But while mutations in this gene account for large percentages of hereditary breast and ovarian cancers, BRCA1 is almost always normal in nonfamilial incidences of these cancers, which form the large majority of cases.