| GS | Games Started (sports statistic) | |
| GS | General Schedule | |
| GS | Gran Sport (Buick) | |
|
| GS | Golden State | |
| GS | Global Sources | |
| GS | Girl Scout | |
| GS | Goldman Sachs Group, Inc. | |
| GS | Green Seal (environmental standard) | |
| GS | Grade School | |
| GS | Gold, Silver | |
| GS | Grand Seiko (Seiko Watch Corp.) | |
| GS | Graduate Student | |
| GS | General Store (various locations) | |
|
| GS | Ghostscript | |
| GS | General Service | |
| GS | General Surgery | |
| GS | Geological Survey | |
| GS | Gold Standard | |
| GS | Giant Slalom | |
| GS | General Support | |
| GS | GuideStar | |
| GS | Gainesville Sun (Gainesville, FL newspaper) | |
| GS | Gas Station | |
| GS | Grand Slam (baseball) | |
| GS | German Shepherd | |
| GS | Ground Station | |
| GS | Generator Set | |
| GS | Game Show | |
| GS | Good Shepherd | |
| GS | Gangnam Style (South Korean rap music) | |
| GS | Gedeputeerde Staten | |
| GS | Gamespot (video game website) | |
| GS | South Georgia and the South Sandwich Islands (ISO country code, top level domain) | |
| GS | Garden State | |
| GS | Glutamine Synthetase (enzyme) | |
| GS | General Study (education) | |
| GS | Ground Support | |
| GS | Gamestop (video game store) | |
| GS | Gameshark | |
| GS | General Secretary (in colleges of India) | |
| GS | Gauss | |
| GS | Good Samaritan | |
| GS | General Science | |
| GS | Glide Slope | |
| GS | Global Studies (education) | |
| GS | Golden Sun (gaming) | |
| GS | Gene Simmons (musician) | |
| GS | Godsmack (band) | |
| GS | Gaza Strip | |
| GS | Good Shot (games) | |
| GS | General Specification | |
| GS | Geprüfte Sicherheit (German: Proved Safety law) | |
| GS | General Staff | |
| GS | Glucosamine Sulfate | |
| GS | Government Security | |
| GS | George Strait (country music artist) | |
| GS | Grade Scale (US federal government wage level) | |
| GS | Gyroscope | |
| GS | Gas Supplier | |
| GS | Galvanized Steel | |
| GS | Game Site | |
| GS | Gleichstrom (German: Direct Current) | |
| GS | George School (Pennsylvania) | |
| GS | Gundam Seed (anime) | |
| GS | Get Smart (1960s TV show) | |
| GS | Guidance System | |
| GS | General Synod | |
| GS | Ground Speed | |
| GS | Gaelic Storm (Celtic band) | |
| GS | Global Solution | |
| GS | Governor's School | |
| GS | Government Systems | |
| GS | Glomerulosclerosis | |
| GS | Graphics and Sound (Apple Computers) | |
| GS | Group Separator | |
| GS | Group Separator (ASCII character 29) | |
| GS | Global Supplier | |
| GS | Geopathic Stress (alleged illness caused by electromagnetivity) | |
| GS | Giant Spider (gaming, Tibia Massive Multiplayer Online RPG) | |
| GS | Grass Seed | |
| GS | Gigasample (audio) | |
| GS | Geronimo Stilton (book series) | |
| GS | Grand Sedan (Lexus) | |
| GS | Group Status (insurance) | |
| GS | Government Surplus | |
| GS | General Solution | |
| GS | Ground System | |
| GS | General Statute | |
| GS | Ground Segment | |
| GS | Guide to the Scriptures | |
| GS | Geochemical Society | |
| GS | Game Spy (game) | |
| GS | Golden Slumbers (Beatles song) | |
| GS | General Systems | |
| GS | Gauss-Seidel (algorithm) | |
| GS | Genso Suikoden (Konami game) | |
| GS | Ground Start (telecommunications) | |
| GS | Gear Score (World of Warcraft) | |
| GS | GameSurge | |
| GS | General Stock | |
| GS | Graded Series | |
| GS | Graceful Shutdown | |
| GS | Gang Show (scout/guide) | |
| GS | Grace Slick (singer) | |
| GS | Gilbert's Syndrome (liver disorder) | |
| GS | Geek Speak | |
| GS | German Silver (rabbit breed) | |
| GS | Snow Pellets (METAR precipitation) | |
| GS | Grip Safety (firearms) | |
| GS | Geomagnetic Field | |
| GS | Government Stock(s) | |
| GS | GeoStrategic | |
| GS | Guidance Section | |
| GS | Guilty Spark | |
| GS | Gestational Sac (intrauterine structure) | |
| GS | Grub Screw | |
| GS | Güzel Sanatlar | |
| GS | Goldshire (gaming) | |
| GS | Geometer's Sketchpad (education) | |
| GS | Griscelli Syndrome | |
| GS | Gandke & Schubert (German software company) | |
| GS | General Surveillance | |
| GS | Groton School (Massachusetts) | |
| GS | Guy Smiley (Sesame Street character) | |
| GS | Greenland to St. Johns (routing destination; US Navy) | |
| GS | Gelände-Strasse (German: Off-Road / On-Road; motorcycles) | |
| GS | Grand Soul (gaming) | |
| GS | General Station | |
| GS | Guest Scientist (program) | |
| GS | Group Station (Oil and Gas) | |
| G-S | Grading and Staging (diagnostic method) | |
| GS | Gelijkstroom (Dutch: Direct Current) | |
| GS | Glide Scope | |
| GS | Gravity Switch | |
| GS | Graphics Synthesiser (Sony PlayStation2) | |
| GS | Galilee Society (Israel) | |
| GS | Generic Switch | |
| GS | Grissom Sara (CSI: Crime Scene Investigation TV show) | |
| GS | Global Shield | |
| GS | Galatasaray Sports Club (Turkey soccer club) | |
| GS | General Satellite Corporation | |
| GS | Geekshelter (website) | |
| GS | Guided Scrambling | |
| G-S | Guanine Nucleotide-Sensitive (biochemistry) | |
| GS | Generator Shelter | |
| GS | Guidance Subsystem | |
| GS | General Support Series | |
| GS | Growth Sire | |
| GS | (USN Rating) Gas Turbine System Technician | |
| GS | Guteral Steel | |
| GS | South Georgia & The South Sandwich Island (ISO country code) | |
| GS | Gulf States Mennonite Conference (Philadelphia, MS) | |
| GS | Gross Sales | |
| GS | Great Sword (Monster Hunter) | |