First, the landmark TAX327 trial of docetaxel demonstrated that, contrary to previous experience,[sup.
What does DXT stand for?
DXT stands for Docetaxel (anticancer agent)
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
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We have 1 other meaning of DXT in our Acronym Attic
- Directory Exchange Server
- Diskless X Station
- Draft XML Specification
- Dx Studio (3D engine)
- DirectX Standard Annotations and Semantics
- Daily Intelligence Summary
- Data Extract
- Deep X Ray Therapy (adjuvant radiotherapy)
- Density Times Thickness
- Digital Exchange for TETRA
Samples in periodicals archive:
BACKGROUND: Since the improvement of chemotherapy with safe molecules is needed for a better efficacy without supplementary toxicity, we investigated the feasibility and tolerability of the combination of docetaxel and curcumin, a polyphenolic derivative extracted from Curcuma long a root.
As there is no universally accepted definition of docetaxel-refractory CRPC patients, two definitions were adopted based on the literature: R1) disease progression while on docetaxel or within 100 days of the last docetaxel dose; and R2) disease progression while on docetaxel or within 50 days of the last docetaxel dose.
A weekly dose of paclitaxel prolongs overall survival of breast cancer patients more effectively than weekly docetaxel or the standard 3-week schedule for either taxane, according to investigators of a randomized trial comparing these adjuvant regimens in nearly 5,000 women.
Clinical benefit with docetaxel plus fluorouracil and cisplatin compared with cisplatin and fluorouracil in a phase III trial of advanced gastric or gastro-esophageal cancer adenocarcinoma: the V-325 Study Group Ajani JA, Moiseyenko VM, Tjulandin S et al.
The study compared various dosages of vandetanib combined with docetaxel to docetaxel by itself.
Lilly argued that pemetrexed fills an unmet need because the only other therapy approved for second-line use, docetaxel (Taxotere), is increasingly being used to treat lung cancer patients initially, making it less likely to be used as second-line therapy, said Lilly consultant Frances Shepherd of the University of Toronto.
Docetaxel - manufactured by Aventis under the name Taxotere - was tested on two groups of women, those with one to three affected lymph nodes and those with four or more.
4] Then the landmark TAX327 trial, published in 2004, showed that a course of chemotherapy based on the taxane docetaxel could extend survival for men with mCRPC (versus mitoxantrone-based chemotherapy).
Docetaxel and prednisone in combination are currently considered the standard of care for men with CRPC with detectable metastatic disease.