What does YadF stand for?

The Company's lead development candidate is a next generation NSAID, CG100649 with a novel mechanism of suppressing COX-2 as well as carbonic anhydrase enzymes for improved cardiovascular, gastrointestinal, and renal safety profiles which is in Phase 2b development for osteoarthritis.

She took acetazolamide, a carbonic anhydrase inhibitor, as prophylaxis against acute mountain sickness.

They cover carbonic anhydrase inhibitors and activators, matrix metalloproteinase inhibitors, bacterial zinc protease inhibitors, and other enzymes containing zinc.

Acetazolamide is an inhibitor of carbonic anhydrase and thus promotes an alkaline diuresis (2).

By adding normal carbonic anhydrase genes designed to work only in guard cells, they were able to restore the CO2-triggered pore-tightening response in mutant plants.

16 Science that tasting fizz begins with the enzyme carbonic anhydrase 4.

A team headed by Charles Zuker, a neuroscientist at Columbia University, found that a class of taste-receptor cells in the tongue respond to carbon dioxide, the gas that gives drinks their fizz, and identified an enzyme called carbonic anhydrase 4 in CO perception.

One such example is carbonic anhydrase IX, which identifies a membranous enzyme/protein whose normal function is to regulate both intracellular and extracellular pH and whose expression is induced by hypoxic conditions.

The warning advises caution when zonisamide is used with other drugs that predispose patients to heat-related disorders, such as carbonic anhydrase inhibitors and drugs that have anticholinergic activity.

Red cell zinc or red cell carbonic anhydrase (CA1) is useful in this differentiation.

Carbonic anhydrase helps red blood cells pick up metabolic waste--carbon dioxide--and drops it off in the lungs to be exhaled.

However, Vaidya says, Finnish researchers have found that carbonic anhydrase -- which helps muscle cells metabolize carbon dioxide -- is released only by damaged tissues other than the heart.

Using mass spectrometry, the team tested the microchip using bovine carbonic anhydrase and was able to effectively identify potent inhibitors to the enzyme.

Studies have shown that nacrein, a 60 kDa protein isolated from the EDTA-soluble organic matrix of both nacreous and prismatic layers of Pinctada maxima, exhibits carbonic anhydrase activity (CA), suggesting that carbonic anhydrase acts to catalyze HC[O.

Caution should be used when Topamax is prescribed with other drugs that predispose patients to heat-related disorders," such as carbonic anhydrase inhibitors and drugs with anticholinergic activity.

Carbonic anhydrase VI (CA VI) is a secretory enzyme that was initially described in the ovine parotid gland and saliva [1].