| CU | Credit Union | |
| CU | Cuba | |
| CU | University of Colorado | |
|
| CU | Columbia University | |
| CU | Close-Up | |
| CU | Cambridge University | |
| CU | Consumers Union (publisher of Consumer Reports) | |
| CU | Close Up | |
| CU | Cameron University | |
| CU | Code de l'Urbanisme (French: Urban Planning Code) | |
| CU | City University (main campus in Washington State) | |
| CU | Copper (Cuprum) | |
| CU | Cubic | |
|
| CU | Control Unit | |
| CU | Coventry University (UK) | |
| CU | Christian Union | |
| CU | Chinese University (Hong Kong) | |
| CU | Catholic University (Washington, DC) | |
| CU | Cornell University | |
| CU | See You (chat) | |
| CU | Certificat d'Urbanisme (French: Urban Planning Certificate) | |
| CU | Clemson University | |
| CU | Champaign-Urbana (Illinois) | |
| CU | Carleton University | |
| CU | Cairo University (Egypt) | |
| CU | Concordia University | |
| CU | Cover Up | |
| CU | Creighton University | |
| CU | Cumulus (cloud formation) | |
| CU | Cornerstone University | |
| CU | Carrie Underwood (singer) | |
| CU | Cooper Union | |
| CU | Commercial Union (insurance company) | |
| CU | Colorado University | |
| CU | Campbell University | |
| CU | Covenant University (Nigeria) | |
| CU | Cubic Capacity (US DoD) | |
| CU | Customs Union (international trade relations) | |
| CU | Clarkson University (Potsdam, NY) | |
| CU | College Union | |
| CU | Cedarville University (Cedarville, OH) | |
| CU | Chulalongkorn University | |
| CU | Colitis Ulcerosa (bowel disease) | |
| CU | Chapman University | |
| CU | Clark University (Worcester, MA) | |
| CU | Condensing Unit (HVAC) | |
| CU | Central Unit | |
| CU | Colgate University | |
| CU | Cultural Understanding | |
| CU | Common User | |
| CU | Civil Union | |
| CU | Cheyney University | |
| CU | Communications Unit | |
| CU | Calcutta University (India) | |
| CU | Common Unit | |
| CU | Comenius University (Bratislava, Slovak Republic) | |
| CU | Chronic Urticaria | |
| CU | Channel Unit | |
| CU | Chittagong University | |
| CU | Computer Unit | |
| CU | Celebrities Uncensored | |
| CU | Claflin University (Orangeburg, SC) | |
| CU | Combat Upgrade (Star Wars Galaxies, MMO gaming) | |
| CU | Century University | |
| CU | Client Utility | |
| CU | Calibration Unit | |
| CU | Crisp Uncirculated (paper currency grading) | |
| CU | Crude Unit | |
| CU | Configuration Update | |
| CU | Columbia Ultimate (collections software) | |
| CU | Concord Law School (online law institution) | |
| CU | Cenhedloedd Unedig (Welsh: United Nations) | |
| CU | Congressional Union (early suffragist movement) | |
| CU | Cattlemen's Union | |
| CU | Correlated Uniqueness (statistical model) | |
| CU | Column Uniform | |
| CU | Combiner Unit | |
| CU | Customer Utilization | |
| CU | Cryptic Union (gaming) | |
| CU | Close Utilization (forestry) | |
| CU | Countermeasures Unit (for weapons of mass destruction; FBI) | |
| CU | Cubana de Aviacion, SA Cuba (IATA airline code) | |
| CU | Coefficient of Utilisation | |