54 US Dollar) Duration: 36 months The basal forebrain (BF) constitutes a major neuromodulatory center, providing extensive projections to the entire forebrain, including all of cortex.
What does BF stand for?
BF stands for Basal Forebrain
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of BF
We have 59 other meanings of BF in our Acronym Attic
- Balance Forward
- Balanced Flue (fireplaces)
- Balefire (gaming)
- Ballast Factor
- Balls Faced (game of Cricket)
- Banco Filipino Savings & Mortgage Bank (Philippines)
- Bangface (London, England neo-rave club)
Samples in periodicals archive:
Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain.
Proof of principle has been provided by evidence of efficacy for intrathecal infusion of nerve growth factor in patients with Alzheimer's disease, although this is a therapy that's clinically impractical as it entails accessing the basal forebrain via stereotactic brain surgery.
Sleep disorders Orexin has been shown to play a prominent role in sleep-wake regulation via actions within certain basal forebrain structures and in sleep/arousal disorders.
Researchers in the neurosciences, psychology, pharmaceuticals, and other specialties introduce the considerations and background of the toxins, then describe examples of using the immunotoxin 192 IgG-saporin to make lesions on the cholinergic basal forebrain, the anti-DBH-saporin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin to produce narcoleptic animals, a variety of saporin conjugates in pain research, and cholera toxin B chain- saporin to produce a model of CNS dymyelination.
NGF primarily affects neurons using the neurotransmitter acetylcholine in the basal forebrain, sensory neurons, and sympathetic neurons that regulate organs such as the heart and lungs.
AD is characterized primarily by episodic memory loss due to loss of cholinergic basal forebrain neurons and their projections to the hippocampus.
The present study found that PCB 77 at both LPCB and HPCB significantly elevated ChAT activity in the basal forebrain and hippocampus.