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This may relate to the cells secreting vascular endothelial growth factors (VEGF), brain-derived growth factors (BDNF), and neurotrophin-3 (NT-3), all of which have potential benefits for the treatment of stroke," said Cesar Borlongan, a professor in the Department of Neurosurgery and Brain Repair.
Insulin also activates other growth factors, including nerve growth factor and brain-derived growth factor, which are neuroprotective, both maintaining neuronal structure and promoting anti-apoptotic pathways (Alkon; Gregory Cole, UCLA, North Hills, USA).