From the clinical case study (1), the reader might infer that the changes in clearance and the volume of distribution are reduced with time, but previous pharmacokinetic investigations have found no indications for such a finding.
What does VD stand for?
VD stands for Volume of Distribution
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of VD
We have 18 other meanings of VD in our Acronym Attic
- Virgins In Denial (band)
- Virtual Directory
- Visite Décennale (French: Defects Visit; nuclear power plant outage)
- Visual Designer (for PowerBasic)
- Viterbi Detector
- Vivens Dedit (Latin: He Gave When Alive, epigraphy)
- Vlade Divac (basketball player)
- Voltage Drop
- Volume Damper (HVAC drawings)
Samples in periodicals archive:
Each drug is listed with its classification, half life, volume of distribution and normal dosage.
Thyroid hormone is exten sively bound to plasma proteins, making the volume of distribution small and plasmapheresis a useful therapeutic modality.
Principal anti-tumor mechanism used by these viruses is a direct cytopathic effect, produced as the virus propagates and spreads from initially infected tumor cells to surrounding tumor cells, achieving a progressively larger volume of distribution and enhanced tumor cell killing.
The most significant findings in the study were that infusion in tissue surrounding the main tumor mass or adjacent to the cavity left after tumor resection more consistently led to a clinically significant volume of distribution than infusion into the main tumor mass.
Volume of distribution gives scientists an idea of how widely a drug would distribute throughout the body -- large volume of distribution means the drug goes into many different kinds of tissues and fluids or is highly bound to plasma proteins in the blood, while small volume of distribution means that the drug is more concentrated in the body.
Even though the IPO market has cooled recently, investment in venture capital has consistently risen over the past few years and so the volume of distributions has grown rapidly.
Following the intravenous infusion, mean plasma clearance was 165 mL/min (range, 70-279 mL/min) and mean steady-state volume of distribution was 76 liters (range, 44-96 liters).