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Factor VII, otherwise known as Stable Factor and Proconvertin, is a vitamin K-dependent glycoprotein that is produced in the liver.
12-16) According to 2014 research, 16 different vitamin K-dependent Gla-proteins have been identified.
Kcentra contains four vitamin K-dependent factors: Factor II (prothrombin), Factor VII, Factor IX and Factor X, as well as antithrombotic Proteins C and S.
With vitamin K deficiency, all vitamin K-dependent factors; specifically factors II, VII, IX and X decrease.
In 1978, the first vitamin K-dependent protein relating to skeletal metabolism was discovered and the significance of vitamin K in bone metabolism became public at the end of the 1990s.
For more than half a century, physicians have been struggling with the seemingly impossible task of dosing vitamin K-dependent anticoagulants ever since they were demonstrated to be beneficial in the treatment of acute myocardial infarction.
of Wisconsin, emeritus) describes the vitamin K-dependent carboxylase, the vitamin K-eposide reductase, a closely associated enzyme, and the identification and function other vitamin K-dependent proteins.
Thromboplastins from different sources and methods of manufacture contain different concentrations and mixtures of components, and this leads to variation in the responsiveness of the reagent; that is, difference in the degree of PT prolongation induced by decreased vitamin K-dependent factor activities.