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The authors believe that the antibody targets a conserved region of the viral coat protein, hemagluttinin, accounting for the extended breadth of activity against multiple, genetically distinct strains.
Molecular Partners has successfully generated DARPins against more than twenty different disease targets, including cell surface receptors, cytokines, proteases, kinases and viral coat proteins.
The new genes include two viral coat proteins and an enzyme.
Unlike other viral protein targets, such as viral coat proteins, the 3C protease is common to all the rhinoviruses and other viruses such as hepatitis A, meningitis and polio.
REMUNE is an HIV-specific investigational immune based therapy consisting of whole killed HIV-1 depleted of gp120 viral coat proteins.
FDA indicates that transgenic viral coat protein protected plants require no premarket approval by FDA.