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Vasoactive intestinal peptide receptor 1 (VPAC1) couples heterotrimeric G proteins, Gas and G[alpha]i, that activate and inhibit adenylate cyclase cAMP production.
50] 11:40 THE FIVE TRANSMEMBRANE VASOACTIVE INTESTINAL PEPTIDE RECEPTOR 1 ISOFORM IS EXPRESSED IN HUMAN BLOOD CD14+ MONOCYTE CELLS.
IK has been shown to decrease expression of an anti-proliferative, G-protein coupled receptor, vasoactive intestinal peptide receptor 1 (VPAC1) when ectopically overexpressed in NIH-3T3 cells.