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What does TNT stand for?

TNT stands for Treating to New Targets (clinical trial)


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Samples in periodicals archive:

Using data from the Treating to New Targets (TNT) study and Incremental Decrease in End Points Through Aggressive Lipid Lowering (IDEAL) study, in which patients were treated with either atorvastatin or simvastatin, researchers were able to examine the relationship between baseline lipoprotein parameters and kidney function in a combined cohort of more than 19,000 patients with coronary heart disease.
In fact, a recent post-hoc analysis of 9,770 patients from the Treating to New Targets study, published in the New England Journal of Medicine, concluded HDL levels were predictive of major cardiovascular events in patients treated with statins, and also observed in patients with LDL levels below the National Cholesterol Education Program's most aggressive target of 70 mg/dL.
NEW YORK -- Improvements in kidney function in patients treated with Lipitor([R]) (atorvastatin calcium) were shown to strongly correlate with a reduced risk of major cardiovascular events in patients with pre-existing cardiovascular disease, according to a post hoc sub-analysis of the five-year Treating to New Targets (TNT) study presented today at the Annual Scientific Sessions of the American Heart Association.
Deedwania and his colleagues pooled data on 21,727 patients from three trials: Treating to New Targets (TNT), which compared 10 mg with 80 mg atorvastatin in patients with stable coronary heart disease and LDL levels below 130 mg/dL (N.