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Prevent alloimmunization and reduce risk of painful and potentially life-threatening transfusion reactions for patients receiving transfusions of red blood cells (RBC)
The HemoDefend platform is based upon CytoSorbents% proprietary hemocompatible porous polymer bead technology and already removes many blood contaminants that can potentially cause transfusion reactions such as free hemoglobin, antibodies, and cytokines.
Fatal hemolytic transfusion reaction due to anti-[Fy.
A mild acute hemolytic transfusion reaction in a patient with alloanti-Ge3: a case report and review of the literature.
The inability to detect clinically significant antibodies could place patients at an increased risk for developing a hemolytic transfusion reaction.
Dermatologic symptoms such as hives and urticaria are typical of an allergic transfusion reaction (ATR).
However, pregnancy-associated plasma protein-A markedly inhibits the haemolytic activity of complement (2), probably explaining the attenuated transfusion reaction in this patient.
Researchers looked at the number of reports of transfusion reactions during the 14-year period, and divided them by the total number of blood components transfused (778, 559).