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Datta specializes in resections for colorectal cancer, including Total Mesorectal Excision (TME), which is the surgical procedure of choice to treat rectal cancers.
Many investigators have found that relatively wound-limiting interventions, such as a laparoscopic cholecystectomy for benign lesions or a laparoscopic total mesorectal excision (TME) for a malignant tumour,[sup.
Advances in surgical techniques, including total mesorectal excision (TME), and chemoradiation have contributed to significantly diminish the local failure rate.
Over 1,800 patients with rectal cancer were randomly assigned to undergo either total mesorectal excision or preoperative radiation therapy and total mesorectal excision.
For the past 2 decades, most colorectal surgeons have viewed radical proctectomy with total mesorectal excision as unnecessarily aggressive for small early rectal tumors confined to the bowel wall.
An interim analysis of data from an ongoing trial of 1,321 rectal cancer patients undergoing total mesorectal excision found no advantage associated with a total dose of 25 Gy given in five fractions over 5-7 days less than 10 days before surgery.