What does TMS stand for?

Thymidylate Synthase

This definition appears very rarely and is found in the following Acronym Finder categories:

Science, medicine, engineering, etc.

Other Resources:

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Samples in periodicals archive:

Results from molecular marker studies in oesophagogastric cancer Markers related to response to 5-FU 5-FU is an inhibitor of thymidylate synthase (TS), an essential enzyme for DNA synthesis [20].

Translational research in oesophagogastric cancer: still a long way ...

5-FU principally acts as a thymidylate synthase inhibitor, meaning that it interrupts the action of this enzyme which is a critical factor in the synthesis of the pyrimidine thymine -- important in DNA replication.

Cancer drug is used by Angiotech as new CVC anti-infective

Their inspiration: thymidylate synthase A, or ThyA, a protein that in a flawed form plays a part in types of cancer.

Songs in the key of life

Pemetrexed is an antifolate/antimetabolite with several molecular targets involved in both pyrimidine and purine neosynthesis: thymidylate synthase (TS), dihydrofolate reductase (DHFR) and glycinamide ribonucleotide formyltransferase (GARFT).

A randomized Phase II trial of pemetrexed plus irinotecan (ALIRI) ...

Cancer drug is used by Angiotech as new CVC anti-infective

Thymidylate synthase (TS) is a homodimer of approximately 72 kDa which catalyzes the reductive methylation of 2-deoxyuridine monophosphate (dUMP) using 5,10-methylenetetrahydrofolate ([CH.

Stabilization of the Inactive Conformation of Human Thymidylate ...

1: Thymidylate synthase (TS) RNA expression in non-small cell lung cancer (NSCLC): Implications for personalizing pemetrexed therapy.

Response Genetics to Present New Data at the 13th World Conference on ...

Elderly patients with fluoropyrimidine and thymidylate synthase inhibitor-resistant advanced colorectal cancer derive similar benefit without excessive toxicity when treated with irinotecan monotherapy.

Use of the folinic acid/5-fluorouracil/irinotecan (FOLFIRI 1) regimen ...