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6,7] The standard treatment for CTEPH is pulmonary thromboendarterectomy (also referred to as PTE, or pulmonary endarterectomy, PEA), a potentially curative surgery that clears clots and scar material from the blood vessels of the lung.
Pulmonary thromboendarterectomy is the treatment of choice but not all patients are eligible for surgery.
Pathophysiology of impaired right and left ventricular function in chronic embolic pulmonary hypertension: changes after pulmonary thromboendarterectomy.
The largest differences in RVUs were demonstrated for carotid thromboendarterectomy and revascularization procedures, including CABG and PTCA.
Also, an embolus from the occluding thrombus into a more distal cerebral artery would not be removed by the thromboendarterectomy and would require thrombolytic therapy or a second, intracranial surgical embolectomy to remove.
The Company previously announced favorable results from a preliminary analysis of a Phase II clinical trial with Cylexin evaluating its ability to reduce reperfusion injury following the surgical removal of chronic blood clots from the lungs in an orphan drug indication, pulmonary thromboendarterectomy (PDE).
Auger, MD, Professor of Clinical Medicine, Research Director, Pulmonary Thromboendarterectomy Program, University of California, San Diego.
CTEPH was diagnosed and pulmonary thromboendarterectomy (PEA) was planned.