Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity.
What does TPMT stand for?
TPMT stands for Thiopurine Methyltransferase
This definition appears very frequently and is found in the following Acronym Finder categories:
- Science, medicine, engineering, etc.
See other definitions of TPMT
We have 4 other meanings of TPMT in our Acronym Attic
- Tree Parity Machine Rekeying Architecture (computer security)
- Theater Patient Movement Requirements Center
- Turbo and Power Machinery Research Center (South Korea)
- Takoma Park Middle School (Maryland)
- Technical Performance Measurement System
- Technology Performance Management Service
- Teleprocessing Management System
- Tire Pressure Monitoring System
- Transaction Processing Management System
- Transition Power and Maintenance Shelter (NEXRAD)
- Tibialis Posterior Myofascial Tightness (heel pain)
- Total Preventive Maintenance Time
- Transaction Processing Monitor Technology
- T1 Performance Monitoring Unit (Hekimian)
- Tomato Planta Macho Viroid
- Tactical Packet Network
- Tatrzanski Park Narodowy (Polish: Tatry Mountains National Park)
- Tennant Profile Network (South Africa)
- The Perspectives Network
- The Pixelgeek Network (website)
Samples in periodicals archive:
Stability of thiopurine metabolites and thiopurine methyltransferase activity in human blood: 11.
ABSTRACT Background: Genetic polymorphisms in thiopurine methyltransferase (TPMT) influence the metabolism of azathioprine (AZA) and 6-mercaptopurine (6-MP) in patients with inflammatory bowel disease (IBD).
An enzyme called thiopurine methyltransferase, or TPMT, normally inactivates the drugs.
The abstracts to be presented include two oral presentations and four poster presentations as follows: Oral Presentations: -- Utility of Thiopurine Methyltransferase Pharmacogenetic Testing and Monitoring of Azathioprine Metabolites in the management of Autoimmune Hepatitis.
Schutz, E, Gummert, J, Mohr, F, Oellerich, M: Azathioprine-induced myelosuppression in thiopurine methyltransferase deficient heart transplant recipient.
Background & objectives: Mercaptopurine, azathioprine, and thioguanine, used as antineoplastic agents and immunosuppressants are catabolized by thiopurine methyltransferase (TPMT) enzyme, which exhibits genetic polymorphism.
Genotyping of eight thiopurine methyltransferase mutations: three-color multiplexing, "Two-Color/Shared" anchor, and fluorescence-quenching hybridization probe assays based on thermodynamic nearest-neighbor probe design.