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The decision and choice of diagnostic tests to evaluate for target organ damage in adolescents with essential hypertension warrant further study to understand the underlying rationale for those decisions and to determine treatment effectiveness," the researchers conclude.
Indeed, hypertensive patients with evidence of target organ damage are well recognized to be at high risk of cardiovascular and cerebrovascular events, and they should be targeted for aggressive blood pressure and risk factor management (3).
With the increase in hypertension in pediatric individuals and the finding of target organ damage in adolescents (for the first time--formerly, it was in texts that individuals did not develop damage to CV system until 20s or 30s), it is clear that all health care professionals should monitor blood pressure in the pediatric population.
The new study's findings are important because "nocturnal nondipping" associated with sleep-disordered breathing (SDB) has been linked to target organ damage and to a poor cardiovascular prognosis (Can.
The extraordinary antioxidant activity and antilipidemic effects of melatonin may enhance the modulation of blood pressure by melatonin and probably play the most important role in the amelioration of target organ damage by chronic melatonin treatment.
[FIGURE 1 OMITTED] Table I shows the demographic characteristics, diabetic control, reported adherence, target organ damage and drug usage differences between the study patients with and without executive impairment.
Anadolu Kardiyol Derg 2007: 7 Suppl 1; 153-8) Key words: hypertension, left ventricular hypertrophy, relative voltage deficit, specific potential of myocardium, target organ damage Introduction Left ventricular hypertrophy (LVH) detected either by electrocardiography (ECG) or echocardiography (EchoCG) in patients with high blood pressure (BP) is defined as an indicator of cardiac target organ damage (C-TOD) (1, 2).
The work covers historical, pathophysiological, and clinical aspects of hypertension, and includes chapters on target organ damage, clinical assessment, treatment, hypertension in special patient groups, hypertension in pregnancy, and hypertensive urgencies and emergencies.