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The study was conducted between June 2010 and December 2011 among overweight and obese patients with symptomatic atrial fibrillation.
In the randomized, placebo-controlled trial, 104 patients presenting with symptomatic atrial fibrillation or atrial flutter of recent onset were assigned to one of three doses of vanoxerine or placebo.
In one, taking fish oil for a year failed to limit recurrent symptomatic atrial fibrillation, a type of irregular heartbeat that significantly raises the risk of stroke.
The primary outcome measures will assess both safety and freedom from documented, symptomatic atrial fibrillation.
About the DISCERN AF Study The prospective, multicenter study included 50 patients with symptomatic atrial fibrillation.
Propafenone extended release capsules are indicated to prolong the time to recurrence of symptomatic atrial fibrillation in patients without structural heart disease.
The findings of the A-4 trial suggest that ablation may help people with frequent, highly symptomatic atrial fibrillation who otherwise would do poorly on AADs.
This phase III randomized, double blind, active controlled, double dummy, multi-center trial enrolled a total of 254 patients with symptomatic atrial fibrillation of 3 to 48 hours duration of which 232 were randomized to receive either BRINAVESS, n=116 (3 mg/kg over 10 minutes; followed by 2 mg/kg over 10 minutes if needed after a 15-minute break) or amiodarone, n=116 (5 mg/kg over 60 minutes, followed by 50 mg over 60 minutes until patient converts).