What does SVR stand for?

The following points should be considered when initiating therapy with PEGINTRON in combination with REBETOL: (1) These indications are based on achieving undetectable HCV RNA after treatment for 24 or 48 weeks and maintaining a Sustained Virologic Response (SVR) 24 weeks after the last dose.

After 48 weeks of treatment, 55 percent of patients had a sustained virologic response.

After week 24 of treatment, 35 percent of patients who achieved a sustained virologic response became virus negative.

A sustained virologic response to hepatitis C treatment is more likely among people who are able to adhere to at least 80% of their full doses of ribavirin and pegylated interferon for at least 80% of the entire duration of therapy.

In both studies, albinterferon alfa-2b, with half the injections, achieved sustained virologic response comparable to that achieved by peginterferon alfa-2a.

Willenbring cited results from three recent studies that showed good sustained virologic response rates in intravenous drug users who relapsed during HCV treatment.

With half the injections, ZALBIN achieved a rate of sustained virologic response comparable to Pegasys in these studies; rates of serious and/or severe adverse events were also comparable.

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced that sustained virologic response (SVR) data from Study C208, which evaluated twice-daily dosing of Vertex's investigational hepatitis C virus (HCV) protease inhibitor telaprevir, will be presented in an oral presidential plenary session at the 60th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) taking place Oct.