Despite hailing from distinctly different backgrounds, country fiddler/singer Krauss and Led Zep's sonic hedgehog move beyond what you might imagine in this foray into rootsy country and folk.
William Jeffery of the University of Maryland at College Park and his colleagues had previously reported that the gene sonic hedgehog controls eye and mouth formation in the freshwater fish Astyanax mexicanus.
NASDAQ: CRIS), a drug development company focused on seeking to develop novel targeted medicines primarily for cancer treatment, today announced that it was notified by one of its corporate partners, Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE), that preliminary data with a protein agonist of the Sonic Hedgehog (Shh) signaling pathway showed promising results in an established, early preclinical cardiovascular animal model.
During embryonic development, the gene sonic hedgehog participates in the formation of the brain, heart, lung, skeleton, and many other tissues and organs.
NASDAQ: CRIS), a therapeutic drug development company, today announced the publication of preclinical data in the journal Circulation, showing that topical Sonic Hedgehog gene therapy accelerated wound healing in an animal model of diabetes.
8 Cell their discovery that proteins from three genes--activin receptor IIa (cAct-RIIa), sonic hedgehog (Shh), and chicken nodal-related 1 (cNR-1)--form a sort of two-pronged biochemical cascade.
