What does SCE stand for?

The researchers looked at three standard indicators of chromosomal damage: structural chromosomal aberrations (breaks in chromosomes), micronuclei (small nuclei consisting of chromosome fragments produced by breakage or whole chromosomes lost from the main nucleus after the cell divides), and sister chromatid exchanges (exchanges of genetic material between a pair of identical chromosomes).

Arsenical compounds are potent clastogens in many cell types inducing chromosomal aberrations, sister chromatid exchanges (SCEs), cell cycle arrest, mitosis disturbance, aneuploidy, cytoskeleton disruption, apoptosis, and chromosomal loss in both human and rodent cells in culture.

Positive selection of FLP-mediated unequal sister chromatid exchange products in mammalian cells.

4-fold increases were found in chromosome aberrations (12 cases), sister chromatid exchanges (11 cases), and micronuclei frequencies (11 cases), respectively.

did not induce any chromosomal aberration in bone marrow cells of mice; there were no significant differences observed in sister chromatid exchange and micronuclei formation tests at the same dose levels.

We measured sister chromatid exchange and chromosomal aberrations to determine human chromosome damage, and for DNA damage, we measured DNA single-strand breaks and DNA-protein cross-links.

In vitro treatment of human lymphocytes with glyphosate and a glyphosate formulation resulted in a significantly higher rate of induction of sister chromatid exchange by the formulated product (Bolognesi et al.

Sister chromatid exchange rate and alkaline comet assay scores in patients with ovarian cancer.