But it was White Blood Cells in 2001 that made their name n the UK and next album Elephant was recorded in London - featuring biggest hit Seven Nation Army - went to number one in the album charts.
The Seven Nation Army singer says, "You get nervous because you want to make sure it's done right and all you have to do is watch a little bit of Davis' work and I thought, there's a great chance of it being done right.
The pair have re-invented rock, by way of proper R'n'B (that's rhythm and blues to you rap-hats) showing it only takes a loose guitar played alongside a keyboard (him) and hard drumming (her) to create classics such as Seven Nation Army and Doorbell.
One knock on his chances is that there could be other front-runners to bother him in the Classic, including, potentially, sprinters McNasty (30-1) and Seven Nation Army (10-1).
These fans were the most fanatical and the Curva was full an hour before kick-off with the Italians chanting along to the thumping bass notes of the White Stripes rock anthem Seven Nation Army.
White Stripes' hit Seven Nation Army was given the Hard-Fi treatment and the boys managed the enormous task of pulling it off without paling in comparison to the original.