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Among the topics are the regulation of transcriptional factor function by targeted protein degradation, assessing sequence-specific DNA binding and transcriptional activity of STAT1 translation factor, detecting modified factors at target gene promoters in the post-translational control of ETS transcriptional factors, and the flow cytometry analysis of transcriptional factors in T lymphocytes.
They address the move toward a universal platform for autologous stem cell gene therapy and also address adenosine deaminase deficiency, insertion of a transgene into Chromosome 19, site-specific integrating vectors, gene targeting, engineering of homing endonucleases and novel sequence-specific DNA binding and modifying, gene targeting mediated by hyper-dependent adenoviral vectors, and multipotent progenitor cells.
9780854043705 Sequence-Specific DNA binding agents.