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Rheumatoid factor positive poly-JIA accounts for less than 10% of JIA and is essentially childhood onset of (adult) rheumatoid arthritis, with characteristic erosive arthritis, classic deformities, and variable presence of rheumatoid nodules.
Patients who were rheumatoid factor positive were more likely than RF-negative cases to have pericardial disease.
Although no significant relationship was found between markers of childhood infection and the presence of rheumatoid factor in men, women who shared a bedroom during childhood had a significantly lower risk of being rheumatoid factor positive (odds ratio 0.
A total of 75% were rheumatoid factor positive, and all had at least six swollen joints, eight tender joints, and elevated C-reactive protein (CRP).
Of the study participants, 593 women had confirmed incident RA, and of those, 82% were rheumatoid factor positive.
Eighty to 90 percent of RA patients seen in a rheumatology setting are rheumatoid factor positive and, despite treatment with a disease-modifying antirheumatic drug (DMARD), sustain significantly more structural damage within the first two years of disease compared to patients who were not rheumatoid factor positive.
Patients' mean age was 55 years, 76% were female, and 82% were rheumatoid factor positive.
Moreover, patients who were rheumatoid factor positive had elevated calprotectin levels as well as high ESRs, modified Sharp scores, and RAAD scores, according to Dr.