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What does RPTD stand for?

Recommended Phase II Dose (pharmaceutical research)


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This definition appears very rarely and is found in the following Acronym Finder categories:

  • Science, medicine, engineering, etc.

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Samples in periodicals archive:
The trial's primary objective is to determine safety, tolerability and recommended Phase II dose, and patients with metastatic solid tumors who are refractory to available therapies or for whom no standard systemic therapy exists will be enrolled.
Sixty-nine adult patients from Spain participated, 15 in the dose escalating part and 54 at the recommended phase II dose.
The maximum tolerated dose and the recommended Phase II dose have not yet been determined.
The recommended Phase II dose was satraplatin at 40mg/m2/day given on days 1-5 and docetaxel at 60mg/m2 given on day 1 of a three-week cycle, without G-CSF, and satraplatin at 50mg/m2/day given on days 1-5 and docetaxel at 70mg/m2 given on day 1 of a three-week cycle with G-CSF.
The trial objectives are to assess safety and to determine the maximum tolerated dose and dose-limiting toxicity by applying a dose-escalation schedule with a limited number of patients and to define the recommended Phase II dose.
Recommended Phase II Dose of MGCD0103 Determined as 90 mg * 53% of Patients Treated with 90 mg Dose Achieved a Clinical Response * Patients with Responses Experienced a 66% Reduction in the Risk of Death Compared to Non-responders ATLANTA, Dec.
Immediately upon determination of a recommended Phase II dose for IMC-A12 combined with gemcitabine and erlotinib, a Phase II multicenter study will begin.
The primary objectives are to determine the safety and tolerability of TM601, to determine the target recommended Phase II dose and the biologically active dose of TM601 when administered intravenously and to study the pharmacokinetics of TM601 at each dose level.

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