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For the study, researchers at the Institute of Medical Science and Jeju National University in Korea analysed the components of young asparagus shoots and leaves to compare their biochemical effects on human and rat liver cells.
The cytotoxic effects observed by exposing rat liver cell to arsenic trioxide depicted different observations; PFT-[alpha] did provide protection to rat liver cells upon exposure to arsenic trioxide: L[C.
Initial experiments are looking at the response of rat liver cells to aflatoxin exposure.
Seglen P0 (1976) Preparation of isolated rat liver cells.
MultiCell's immortalized human liver cells for drug discovery, toxicology and pharmacogenomic studies may offer leading pharmaceutical companies a much more cost effective alternative than the rat liver cells and primary human cells traditionally used for these studies.
MultiCell's immortalized human liver cells for drug discovery, toxicology and pharmacokinetic studies may offer leading pharmaceutical companies a more effective alternative to the rat liver cells and primary human cells used for these studies today.
The research team, from the University of California, San Diego (UCSD), used electrochemistry to etch the pores and then circuit-making techniques to add 15-micron-wide wells, each just big enough to house a rat liver cell.
These data demonstrate a number of anti-fibrogenic properties for SCY-635 in isolated human and rat liver cells and suggest that the observed effect is mediated through the TGF-beta signaling pathway.