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22, 2014 /PRNewswire/ -- Idiopathic Pulmonary Hypertension Global Clinical Trials Review, H2, 2014
Despite the rising number of people diagnosed with the disease worldwide, pulmonary hypertension has been a historically neglected disease.
ATLANTA--Riociguat, a novel first-in-class guanylate cyclase stimulator, significantly improved 6-minute walk distance in patients with inoperable chronic thromboembolic pulmonary hypertension as well as in patients with symptomatic pulmonary arterial hypertension.
Chronic thromboembolic pulmonary hypertension during pregnancy is uncommon but is associated with maternal mortality in excess of 35% (2-4).
Pulmonary hypertension is an uncommon vascular condition in which the pulmonary vessels become narrowed, and the blood pressure in the pulmonary circulation increases.
Pulmonary hypertension due to undiagnosed wide atrial septal defect (ASD) at the older age was the etiology of this giant aneurysm.
1) From the time of diagnosis, the 1-, 3-, and 5-year survival rates noted in the National Institute of Health Registry on Primary Pulmonary Hypertension were 77%, 41%, and 27%, respectively.
Human herpesvirus 8 (HHV-8) antibodies were detected in 1 of 33 patients with pulmonary hypertension (including in 1 of 16 with idiopathic pulmonary arterial hypertension), 5 of 29 with cystic fibrosis, and 3 of 13 with interstitial lung disease.