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Fifty-four people diagnosed with CFS or fibromyalgia and 23 controls were given five tests to evaluate their blood: fibrinogen (FIB), prothrombin fragment 1 + 2 (F1 + 2), thrombin/antithrombin complexes (T/AT), soluble fibrin monomer (SFM), and platelet activation by flow cytometry (PA) using CD62P and ADP.
Estimating adjusted odds ratios for the fourth versus first quartile of each biomarker using logistic regression, they compared baseline and 1-month levels of four inflammatory makers (high-sensitivity C-reactive protein, interleukin-6, serum amyloid A, and amyloid P) and two coagulation markers (D-dimer and prothrombin fragment 1 + 2), Dr.
7) studied an enzyme-linked immunosorbent assay with use of monoclonal capture antibody for prothrombin fragment 1.