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We used Cox proportional hazards models to estimate hazard ratios and 95% confidence intervals for the association of baseline and follow-up measurements of serum glucose and insulin with breast cancer risk.
The association between the serum concentrations of lycopene [alpha]-carotene, [beta]-carotene, [alpha]-tocopherol, and retinol and the risk of strokes was studied using Cox proportional hazards models.
In a proportional hazards model that adjusted for baseline differences in age and gender, treatment with an anti-TNF agent reduced the rate of CV events by about half, a statistically significant effect, said Dr.
1) The primary analysis employed a Cox proportional hazards model to compare outcomes in subjects with H/M of <1.
I use the semi-parametric Cox proportional hazards model because no assumption is made about the underlying shape of the baseline hazard.
Cox proportional hazards models were used to assess whether androgen deprivation therapy with GnRH agonists, oral antiandrogens (drugs that block the action of hormones), the combination of the two, or orchiectomy (removal of the testicles) were associated with diabetes, coronary heart disease, myocardial infarction, sudden cardiac death, or stroke, after adjustment for patient and tumor characteristics.
The relative risk of death as a function of each transition index was calculated using proportional hazards models, adjusting for age, gender, body mass index, race, hypertension, cardiovascular disease, smoking status, respiratory disturbance index and arousal index.
We retained variables in proportional hazards models that had P values for their coefficients [less than or equal to] 0.