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What does PRNP stand for?

PRNP stands for Prion Protein


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Samples in periodicals archive:

When these normal cellular prion precursors convert to pathogenic prion proteins, the transmissible conformations are characterized by [beta]-pleated sheets rather than the normal [alpha]-helix structure, and they do not elicit an immune response (4).
RT-QuIC, developed in recent years, detects when normal prion protein converts to an abnormal form The resulting test-which they call enhanced QuIC (eQuIC)-improves prospects for routinely detecting low levels of abnormal prions in tissues, fluids or environmental samples such as soil.
Prion protein is a natural cellular protein that can become misfolded into infectious particles and cause bovine spongiform encephalopathy (BSE, or "mad cow disease") and a lethal variant of Creutzfeldt-Jakob disease (vCJD) in humans.
22 Kyodo (EDS: UPDATING WITH RELEASE OF STUDY AT SOCIETY IN 2ND GRAF) A team of researchers said Tuesday that they recently succeeded in delaying the onset of symptoms of prion disease, widely known for brain-wasting effects in mad cow disease, by inoculating mice with normal prion proteins taken from other animals.