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In the same way, the treatment of females with raloxifene, a selective estrogen receptor modulator, during four weeks before the mating, had induced increase of the weight of younglings at the postnatal day 1 (HOYT et al.
Rats were observed from postnatal day 1 to 25 for the age of the appearance of physiological markers (pinna detachment, inscisor's eruption, eye opening) and acquisition of reflexes (surface righting, visual placing, reflex suspension, negative geotaxis).
5wk or 9wk forebrain, at passage 4-28, labelled with Bromo-deoxy-uridine (1uM, 48 hours), were transplanted to the postnatal day 1 (P1) rat CNS, in either the hippocampus, striatum, midbrain, cerebellum or spinal cord.