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Samples in periodicals archive:
The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion for Jakavi (ruxolitinib) for the treatment of adult patients with polycythemia vera (PV) who are resistant to or intolerant of hydroxyurea.
Incyte's (Nasdaq: INCY-Free Report) sole marketed product, Jakafi, gained approval for a rare and progressive blood cancer - polycythemia vera (PV) C in the U.
Dr Alessandro Vannucchi will present the promising results of a Phase III trial for polycythemia vera patients.
This report looks at the treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH), Idiopathic Thrombocytopenic Purpura (ITP), Myelodysplastic Syndrome (MDS), Myelofibrosis (MF) and Polycythemia Vera (PV), acquired orphan blood diseases which result in a sufferer's body not producing blood correctly.
Myeloproliferative neoplasms (MPNs) (6) are a group of hematologic malignancies that include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF).
Splenic rupture following administration of thrombolytic agents has been reported in the presence of myeloproliferative disorders, such as polycythemia vera (7) and in those with splenomegaly secondary to infection (8).
Primary polycythemia relates to defects in erythroid progenitor cells (EPCs), with polycythemia vera being the most common form (7), (8).
The 2008 WHO classification of MPNs has added new entities, including chronic myelogenous leukemia, Philadelphia chromosome-positive (CML); chronic neutrophilic leukemia (CNL); polycythemia vera (PV); primary myelofibrosis (PMF); essential thrombocythemia (ET); chronic eosinophilic leukemia, not otherwise specified (CEL/NOS); mastocytosis; and myeloproliferative neoplasm, unclassifiable (MPN-U).