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What does PLEK stand for?

PLEK stands for Pleckstrin

This definition appears somewhat frequently and is found in the following Acronym Finder categories:

  • Science, medicine, engineering, etc.

Samples in periodicals archive:

signal transduction processes (centaurin, delta 1; NCOA2; pleckstrin and Sec7 domain containing 3; protein phosphatase 2, regulatory subunit B [B56], [gamma] isoform), transcriptional regulation (NCOA2; POU domain, class 2, transcription factor 1; ETS variant gene 3), and cell proliferation pathways (hypothetical protein FLJ36090, epidermal growth factor receptor pathway substrate 15).
PIK3CA encodes p110, the catalytic subunit of the phosphatidylinositol 3-kinase (PI3K), which phosphorylates the phosphoinositide-3,4-diphosphate [PtdIns(3,4)P2] to Ptd-Ins(3,4,5)P3, both messenger molecules that regulate the localization and function of multiple effectors by binding to their specific pleckstrin homology domains.
[11] Human genes: GSTP1, glutathione-S-transferase pi; RARB, retinoic acid receptor [beta]; APC, adenomatous polyposis coli; ACTB, [beta]-actin; EDNRB, endothelin receptor type B; RASSF1, Ras association (RalGDS/AF-6) domain family member 1; CDKN2A, cyclin-dependent kinase inhibitor 2A (formerly p16); PSCD2, pleckstrin homology, Sec7 and coiled-coil domains 2 (formerly ARF); MGMT, O-6-methylguanine-DNA methyltransferase.
Abbreviations: AM, alveolar macrophages; PA, Pseudomonas aeruginosa; GST, glutathione S transferase; YFP, yellow fluorescent protein; GFP, green fluorescent protein; PH, pleckstrin homology domain, Lyn, v-yes yamaguchi sarcoma related gene / protein; PI3K, phosphoinositol -3- kinase; Akt, protein kinase B; MHS, murine alveolar macrophage cell line from ATCC.
Among the topics are inositol lipids and RTPC channel activation, pleckstrin homology domains and phospho-inositides, inositol polyphosphate kinases as regulators of nuclear function, and the evolution of the diverse biological roles of inositols.