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Decreased platelet function has also been observed with whole blood flow cytometry after in vitro activation (22) and when using the Platelet Function Analyzer (PFA-100) (30).
Rapid assessment of glycoprotein IIb/IIIa blockade with the platelet function analyzer (PFA-100) during percutaneous coronary intervention.
Investigators at Oxford (England) University have shown that the agreement among the results of the platelet function analyzer (PFA-100), VerifyNow-ASA assays, and LTA testing remained poor among 72 patients still on low-dose aspirin therapy 1 year after first being tested, with only one patient identified as a nonresponder by all three tests (Platelets 2008;19:119-24).
An initial run of blood specimens through a platelet function analyzer identified a prolonged closure time for 17 of the girls (57%).
In contrast, in patients with von Willebrand disease (VWD) type I and borderline to normal ristocetin-cofactor (von Willebrand factor [VWF]:RCo) activity, collagen receptor density correlates inversely with closure time in a high-shear-stress system, that is, the Platelet Function Analyzer (PFA-100, Dade-Behring, Deerfield, Ill).
announced today that they have added the PFA-100(R) Platelet Function Analyzer to their existing purchasing agreement for hemostasis products.
Company begins international distribution of its AggreGuide(TM) A-100 platelet function analyzer HOUSTON -- Aggredyne, Inc.
Platelet function was assessed with the PFA-100 platelet function analyzer (Siemens Healthcare Diagnostics, Deerfield, IL, USA).